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2013-09-07 - Colloque/Présentation - poster - Anglais - 1 page(s)

Rubio Magnieto Jenifer , Thomas amandine, Richeter S., Ahmad Mehdi, Lazzaroni Roberto , Dubois Philippe , Clement Sebastien, Surin Mathieu , "Insights into the self-assembly of cationic conjugated polymer - DNA hybrid structures" in mnpc'13 : Matériaux et Nanostructures Pi-Conjugués, Annecy, France, 2013

  • Codes CREF : Chimie des polymères de synthèse (DI131C)
  • Unités de recherche UMONS : Chimie des matériaux nouveaux (S817)
  • Instituts UMONS : Institut de Recherche en Science et Ingénierie des Matériaux (Matériaux), Institut de Recherche sur les Systèmes Complexes (Complexys)
  • Centres UMONS : Centre d’Innovation et de Recherche en Matériaux Polymères (CIRMAP)

Abstract(s) :

(Anglais) Water-soluble -conjugated polyelectrolytes (CPEs) have been recently considered as good candidates for developing aqueous optical sensing systems since their optical response is very sensitive to minor perturbations to their conformation and assembly.1 In this frame, we have synthesized CPEs based on cationic poly(3-hexylthiophenes) (P3HT-R)2 with various cationic groups in the side chain (R = imidazolium, ammonium, phosphonium or pyrdinium). We have studied the self-assembly of DNA with these cationic P3HTs, which constitute promising systems for biomedical applications. By means of (chir)optical spectroscopy, we show that DNA and conjugated polymer chains self-assemble in chiral supramolecular duplex structures. They show specific induced circular dichroism signatures ruled by the DNA sequence and topology. Investigating the effects of temperature and molar ratio brings further understanding of their self-assembly and supramolecular organization.