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2010-01-11 - Article/Dans un journal avec peer-review - Anglais - 9 page(s)

Spasova M., Manolova Nevena, Paneva Dilyana, Mincheva Rosica , Dubois Philippe , Rashkov Iliya, Maximova V., Danchev Dobri, "Novel polylactide stereocomplex-based electrospun materials possessing surface with antibacterial and haemostatic properties" in Biomacromolecules, 11, 1, 151-159

  • Edition : American Chemical Society (DC)
  • Codes CREF : Chimie macromoléculaire (DI1315), Catalyses hétérogène et homogène (DI1334)
  • Unités de recherche UMONS : Matériaux Polymères et Composites (S816)
  • Instituts UMONS : Institut de Recherche en Science et Ingénierie des Matériaux (Matériaux)
Texte intégral :

Abstract(s) :

(Anglais) Novel fibrous materials of stereocomplex between high-molecular-weight poly(d- or l-)lactide (HMPDLA or HMPLLA) and diblock copolymers consisting of poly(l- or d-)lactide and poly(N,N-dimethylamino-2-ethyl methacrylate) blocks, respectively (PLLA-block-PDMAEMA or PDLA-block-PDMAEMA), were prepared by solution electrospinning. Fibers with mean diameters ranging from 1400 to 1700 nm were obtained. The stereocomplex formation was evidenced by differential scanning calorimetry (DSC) and X-ray diffraction (XRD) analyses. Annealing at 100 °C for 8 h resulted in the appearance of crystalline peaks at 2? values of 12, 21, and 24° for PLA stereocomplex. X-ray photoelectron spectroscopy (XPS) analyses revealed the gradient composition of the fibers with a surface enriched in tertiary amino groups from PDMAEMA blocks. The availability of tertiary amino groups imparts hemostatic and antibacterial properties to the stereocomplex fibrous materials, as indicated by the performed tests on blood cells and on pathogenic microorganisms.

Notes :
  • (Français) Publié en ligne le 30 novembre 2009
Identifiants :
  • DOI : 10.1021/bm901016y