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2019-09-27 - Colloque/Présentation - poster - Anglais - 1 page(s)

Simoes Loureiro Isabelle , Gayraud Frédérique, Frouin Camille, Colette Cynthia, Lefebvre Laurent , Barkat-Defradas Mélissa, "Lexico-semantic deterioration in Alzheimer's disease inversely mirrors its acquisition in childhood." in Exling, 10th International Conference of Experimental Linguistics, 25-27 septembre 2019., Lisbonne, Portugal, 2019

  • Codes CREF : Psychopathologie (DI3513), Neurosciences cognitives (DI4296), Sciences cognitives (DI4290), Psychologie cognitive (DI4211)
  • Unités de recherche UMONS : Psychologie cognitive et Neuropsychologie (P325)
  • Instituts UMONS : Institut de recherche en sciences et technologies du langage (Langage), Institut des Sciences et Technologies de la Santé (Santé)
  • Centres UMONS : Centre de recherche interdisciplinaire en Psychophysiologie et Electrophysiologie de la cognition (CIPsE), Mind & Health (CREMH)
Texte intégral :

Abstract(s) :

(Anglais) Lexical deterioration in Alzheimer’s disease Frédérique Gayraud1, Isabelle Simoes Loureiro², Camille Frouin1, Cynthia Collette², Laurent Lefebvre², Melissa Barkat-Defradas3 1Laboratoire Dynamique du Langage, University of Lyon & CNR, France 2 2Cognitive Psychology and Neuropsychology dept, University of Mons, Belgium 3Institut des Sciences de l’Évolution de Montpellier, France Abstract This research aimed to assess the validity of the retrogenesis hypothesis applied to the lexico-semantic knowledge. According to this hypothesis neurodegenerative mechanisms would reverse the order of acquisition in normal development. We present two studies comparing the development and loss of semantic knowledge. Study 1 compares the development of semantic knowledge about objects in children aged from 5 to 9 years old and its loss in Alzheimer’s disease. Study 2 compares the performances of children and patients with Alzheimer’s disease in a picture naming task. Both studies exhibited mirrored evolution of semantic knowledge extending the retrogenesis theory to lexico-semantic knowledge. Key words: retrogenesis, Alzheimer’s disease, semantic knowledge, lexical access