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2007-07-09 - Article/Dans un journal avec peer-review - Anglais - 15 page(s)

Yancheva Elena, Paneva Dilyana, Danchev Dobri, Mespouille Laetitia , Dubois Philippe , Manolova Nevena, Rashkov Iliya, "Polyelectrolyte complexes based on (quaternized) poly[2-dimethylamino)ethyl methacrylate] : behaviour in contact with blood" in Macromolecular Bioscience, 7, 7-8, 940-954

  • Edition :
  • Codes CREF : Chimie macromoléculaire (DI1315), Catalyses hétérogène et homogène (DI1334)
  • Unités de recherche UMONS : Matériaux Polymères et Composites (S816)
  • Instituts UMONS : Institut de Recherche en Science et Ingénierie des Matériaux (Matériaux)
Texte intégral :

Abstract(s) :

(Anglais) Polyelectrolyte complexes (PECs) between (quaternized) poly[2-(dimethylamino)ethyl methacrylate] (PDMAEMA) and (crosslinked) N-carboxyethylchitosan (CECh) or poly(2-acrylamido-2-methylpropane sodium sulfonate) (PAMPSNa) were prepared and characterized in terms of their stability, equilibrium water content, and surface morphology. The evaluation of the behavior of the studied PECs in contact with blood revealed that the (crosslinked) CECh/(quaternized) PDMAEMA complexes had lost the inherent PDMAEMA cytotoxicity but still preserved haemostatic activity. In contrast, the complex formation between (quaternized) PDMAEMA and PAMPSNa allowed the preparation of materials with improved blood compatibility.

Notes :
  • (Anglais) Publié en ligne le 19 juin 2007
  • (Anglais) Lecture en ligne: http://onlinelibrary.wiley.com/doi/10.1002/mabi.200700056/pdf
Identifiants :
  • DOI : 10.1002/mabi.200700056