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2017-11-26 - Article/Dans un journal avec peer-review - Anglais - 20 page(s)

Guo Tuan, Gonzalez Vila Alvaro , Loyez Médéric , Caucheteur Christophe , "Plasmonic Optical Fiber-Grating Immunosensing: A Review" in MDPI Sensors, 17(12), 2732, 10.3390/s17122732

  • Codes CREF : Optique des fibres (électromagnétisme) (DI1252)
  • Unités de recherche UMONS : Electromagnétisme et Télécommunications (F108)
  • Instituts UMONS : Institut des Biosciences (Biosciences)

Abstract(s) :

(Anglais) Plasmonic immunosensors are usually made of a noble metal (in the form of a film or nanoparticles) on which bioreceptors are grafted to sense analytes based on the antibody/antigen or other affinity mechanism. Optical fiber configurations are a miniaturized counterpart to the bulky Kretschmann prism and allow easy light injection and remote operation. To excite a surface plasmon (SP), the core-guided light is locally outcoupled. Unclad optical fibers were the first configurations reported to this end. Among the different architectures able to bring light in contact with the surrounding medium, a great quantity of research is today being conducted on metal-coated fiber gratings photo-imprinted in the fiber core, as they provide modal features that enable SP generation at any wavelength, especially in the telecommunication window. They are perfectly suited for use with cost-effective high-resolution interrogators, allowing both a high sensitivity and a low limit of detection to be reached in immunosensing. This paper will review recent progress made in this field with different kinds of gratings: uniform, tilted and eccentric short-period gratings as well as long-period fiber gratings. Practical cases will be reported, showing that such sensors can be used in very small volumes of analytes and even possibly applied to in vivo diagnosis.