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2006-09-01 - Article/Dans un journal avec peer-review - Anglais - 12 page(s)

Dyachenko N.S., Nosach L.N., Yu Povnitsa O., Kuz’min V.E., Artemenko A.G., Lozitskaya R.N., Basok S.S., Alexeeva I.V., Zhovnovataya V.L., Vanden Eynde Jean-Jacques , "Structure-antiadenoviral Activity of Nitrogen Containing Macroheterocycles and their Analogues" in Ukrainian Microbiol. J, 68, 5, 69 – 80

  • Codes CREF : Chimie organique (DI1313)
  • Unités de recherche UMONS : Chimie organique (S836)
Texte intégral :

Abstract(s) :

(Anglais) The search for the inhibitors of adenoviruses has been performed among the substances of new class NCM (nitrogen containing macroheterocycles) and their analogues that have high potential of pharmacological properties. We have found a number of NCM and their derivatives that inhibit the reproduction of adenoviruses to various degrees. For the prediction of NCM structure with antiadenoviral activity we have performed the computer modeling using QSAR approach on the basis of simplex representation of molecular structure (SiRMS).

Identifiants :
  • PMID : 17388122