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2018-05-18 - Colloque/Présentation - poster - Anglais - 1 page(s)

Simoes Loureiro Isabelle , Lefebvre Laurent , "The mini-SQK (Semantic knowledge deterioration) : a new tool to screen semantic deterioration in alzheimer's disease." in BAPS 2018-Belgian Association for Psychological Sciences., Gent, Faculty of Psychological and Educational Science.18th May. , Belgique, 2018

  • Codes CREF : Psychopathologie (DI3513), Neurosciences cognitives (DI4296), Sciences cognitives (DI4290), Psychologie cognitive (DI4211)
  • Unités de recherche UMONS : Psychologie cognitive et Neuropsychologie (P325)
  • Instituts UMONS : Institut de recherche en sciences et technologies du langage (Langage), Institut des Sciences et Technologies de la Santé (Santé)
  • Centres UMONS : Mind & Health (CREMH)
Texte intégral :

Abstract(s) :

(Anglais) THE MINI-SQK (SEMANTIC KNOWLEDGE DETERIORATION) : A NEW TOOL TO SCREEN SEMANTIC DETERIORATION IN ALZHEIMER’S DISEASE Simoes Loureiro, Isabelle (1) & Lefebvre, Laurent (1) (1) Cognitive psychology and neuropsychology department, Institute of health sciences and technologies, University of Mons Correspondence: Isabelle Simoes Loureiro, Cognitive psychology and neuropsychology department, University of Mons (UMONS), Place du Parc, 18, 7000, Mons. Email: isabelle.simoesloureiro@umons.ac.be The breakdown of semantic memory appears early in Alzheimer’s disease (AD). Lexico-semantic difficulties (e.g. difficulties in retrieving words and their meaning) are among the first symptoms of the disease. However, semantic knowledge is not always investigated in the neuropsychological assessment and is rather reflected through non-specific semantic measurements as through naming tasks. In order to screen this lexico-semantic decline, we propose the mini-SKQ, a Semantic Knowledge Questionnaire. Mini-SKQ explores semantic impairments in AD patients with 12 questions selected from the SKQ, a previous and longer version of the test, proposed initially by Laiacona et al. (1993), and revised in a French version by Simoes Loureiro and Lefebvre (2015). We administer mini-SKQ to 77 participants, 39 AD and 38 healthy old people. Results showed a significant difference between the groups : AD made significantly more errors than healthy old people. The Receiver Operating Characteristic (ROC) analysis established the optimal cut-off score of the mini-SKQ at 3 errors (sensitivity 61,4%, specificity 89,5%) in differentiating between AD patients and healthy old people. The Mini-SKQ is a fast and easily administered questionnaire. Results indicated favorable indicators to screen semantic knowledge. These first observations underlines that mini-SKQ could potentially be attractive for screening semantic memory deterioration. Laiacona M, Barbarotto R, Trivelli C, Capitani E. Dissociazoni semantiche intercategoriali descrizione di una batteria standardizzata e dati normativi. Archivio di Psicología, Neurología e Psichiatria, 1993 ; 54 : 209-48. Simoes Loureiro, I., & Lefebvre, L. Le QCS : questionnaire de connaissances sémantiques pour déterminer le stade de détérioration sémantique chez les patients atteints de la maladie d’Alzheimer. Gériatrie et Psychologie Neuropsychiatrie Du Vieillissement, 2015 ; 13(2), 225–33. Keywords (3): Alzheimer’s disease, Semantic breakdown, Screening tool